Retinitis Pigmentosa (Generalized Rod–Cone Dystrophies)
*The typical features include:
-Waxy pallor of the optic nerve.
-Narrowing of retinal arterioles
-A generalized mottling and moth-eaten pattern to the retinal pigment epithelium(RPE), often with bony spicule pattern of intraretinal pigment located in the midperiphery.
*A variety of clinical manifestations include:
– Cystoid macular edema, epiretinal membrane formation, optic nerve drusen.
-A Coats’-like retinal vascular response, and posterior subcapsular
cataracts. Veils, condensation and scattered pigmentary
cells may be seen in the vitreous.
*Systemic diseases may be associated with retinitis pigmentosa, and these include:
-Hearing loss, metabolic disorders, neurological syndromes,
and renal or hepatic entities.
*The typical form of retinitis pigmentosa begins with night blindness (nyctalopia) and problems with dark adaptation.