Congenital Hypertrophy of RPE ( CHRPE )
By Dr.Ameen Marashi
48 year old with impaired vision in his left eye 6/20 where the right eye examination yielded no significant information.
Please write investigation and DDx and Ds
By Dr.Mohamed Alaa juxtapapillary diffuse solitary congenital hypertrophy of RPE.
By Dr.Mostafa Eisa Huge CHRPE with depigmented lacunae.
Retinal pigment epithelial hypertrophy can be diagnosed by ophthalmic examination. This will include a careful history for familial colon disease (polyposes). The eye examination will concentrate on the appearance of the retinal pigment epithelial hypertrophy. These lesions tend to be black or atrophic. They may be surrounded by a halo of less pigmented tissue or exhibit a sharp demarcation line.
Ultrasonography typically shows that RPE hypertrophy is flat to minimally elevated, normal or slightly hyper-reflective.
Fluorescein angiography of RPE hypertrophy typically demonstrates blockage of fluorescence (except in the areas of atrophy which are hyperfluorescent).